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Hermansen K et al. – Whichever basal–bolus insulins were previously used, switching to insulin detemir as the basal insulin component resulted in significant lowering of hypoglycaemia, HbA1c, FPG and bodyweight over a period of 6 months in patients with type 1 or 2 diabetes. Switching to an all–analogue regimen may be the most effective option when moving patients from human insulin–based basal–bolus regimens.

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