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See Latest ArticlesIdentification and characterization of novel polymorphisms in the basal promoter of the human transporter, MATE1
Pharmacogenetics and genomics, 09/25/09
Ha Choi J et al. – The study suggests that the rate of transcription of MATE1 is regulated by AP–1 and AP–2rep and that a common promoter variant, g.–66T>C may affect the expression level of MATE1 in human kidney, and ultimately result in variation in drug disposition and response.
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