Pharmacy Medical News about Nicotinamide Mononucleotide

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Nicotinamide glycolates antagonize CXCR2 activity through an intracellular mechanism
Journal of Pharmacology and Experimental Therapeutics, 10/08/09

Maeda DY et al. – The data support a mechanism wherein the nicotinamide glycolate ester serves as a lipophilic precursor that efficiently translocates into the intracellular neutrophil space to liberate the active acid form of the pharmacophore, which then acts at an intracellular site.

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Topical nicotinamide modulates cellular energy metabolism and provides broad-spectrum protection against ultraviolet radiation-induced immunosuppression in humans
British Journal of Dermatology, 10/14/09 Relevance Score: 42%

The relationship of visfatin/pre–B-cell colony-enhancing factor/nicotinamide phosphoribosyltransferase in adipose tissue with inflammation, insulin resistance, and plasma lipids
Metabolism-Clinical and Experimental, 10/09/09 Relevance Score: 42%

Nicotinamide inhibits Propionibacterium acnes-induced IL-8 production in keratinocytes through the NF-kB and MAPK pathways
Journal of Dermatological Science, 10/06/09 Relevance Score: 42%