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Hollow spherical nanoparticulate aggregates as potential ultrasound contrast agent: shell thickness characterization
Drug Development and Industrial Pharmacy, 10/07/09
Hadinoto K et al. – The results indicate that the hollow microspheres size varies between 2 and 10 (Micrometre) having S/R ratio between 2% and 4%, where the smaller size particles exhibit a higher S/R ratio. The resultant S/R ratio is found to be more influenced by process parameters acting at the nanoparticle scale than by the spray drying operating condition.
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