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Moise PA et al. – The decrease in vancomycin treatment efficacy that is accompanying increases in vancomycin minimum inhibitory concentration within the susceptible range has led to the suggestion that vancomycin is losing its potency in treating serious Staphylococcus aureus infections. Understanding the clinical importance of the microbiological effects of glycopeptides on bacterial lipopeptides and lipoglycopeptides will be crucial in treating serious meticillin–resistant S aureus infections.

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