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Identification of a novel CYP2C19-mediated metabolic pathway of S-citalopram in vitro
Drug Metabolism and Disposition, 10/05/09
Rudberg I et al. – Identification of SCIT PROP as a metabolic pathway catalyzed by CYP2C19 might explain why impaired CYP2C19 activity has substantially larger effect on SCIT exposure than estimated from in vitro data based solely on formation of SDCIT.
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