Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. 2008 Exclusive Survey—Earnings: Good news for primary care income 3. Medicare pay-for-reporting effort draws fire from frustrated doctors 4. Debunking Myths in the US Healthcare System 5. Statins and cancer risk
Your Article Summary
Hypoxia induced paclitaxel resistance in human ovarian cancers via hypoxia-inducible factor 1alpha
Journal of Cancer Research & Clinical Oncology, 09/24/09
Huang L et al. – HIF–1alpha, stimulated by hypoxia, exerts a pivotal role in chemoresistance by G0/G1 arrest. Eliminating hypoxic conditions or silencing HIF–1alpha by siRNA might provide a potent tool to enhance paclitaxel effectiveness in treatment of human ovarian cancer.
Related Articles
Stress hormones mediate drug resistance to paclitaxel in human breast cancer cells through a CDK-1-dependent pathway
Psychoneuroendocrinology, 10/22/09
Relevance Score: 67%
Potential predictive markers of chemotherapy resistance in stage III ovarian serous carcinomas
BMC Cancer, 10/21/09
Relevance Score: 66%
Dose Density and Altered Scheduling of Adjuvant Chemotherapy in Ovarian Cancer: Teaching Old Dogs New Tricks
Discovery Medicine, 11/17/09
Relevance Score: 65%
Deletion of PTEN Promotes Tumorigenic Signaling, Resistance to Anoikis, and Altered Response to Chemotherapeutic Agents in Human Mammary Epithelial Cells
Cancer Research, 11/02/09
Relevance Score: 65%
Anthracycline- and/or taxane-resistant breast cancer: Results of a literature review to determine the clinical challenges and current treatment trends
Clinical Therapeutics, 10/15/09
Relevance Score: 64%
Today in Basic Science...keeping you current
Receive free subspecialty "5-minute updates" via email
Lipoxin A4 reduces lipopolysaccharide-induced inflammation in macrophages and intestinal epithelial cells through inhibition of NF-kB activation
Journal of Pharmacology and Experimental Therapeutics, 11/25/09
A Conserved Motif in the Membrane Proximal C-Terminal Tail of Human Muscarinic M1 Acetylcholine Receptors Affects Plasma Membrane Expression
Journal of Pharmacology and Experimental Therapeutics, 11/25/09
The Basic Helix-loop-helix Proteins DEC1 and DEC2 Function as Corepressors of Retinoid X Receptors
Molecular Pharmacology, 11/25/09
Today in Chemotherapy/Oncology...keeping you current
Receive free subspecialty "5-minute updates" via email
Valproic acid restores ERalpha and antiestrogen sensitivity to ERalpha-negative breast cancer cells
Molecular and Cellular Endocrinology, 11/25/09
N2 Disease in Patients With Head and Neck Squamous Cell Cancer Treated With Chemoradiotherapy
Archives of Otolaryngology, 11/25/09
Salvage treatment with upfront melphalan 100 mg/m2 and consolidation with novel drugs for fulminant progression of multiple myeloma
Annals of Hematology, 11/24/09
Today in Drug Resistance...keeping you current
Receive free subspecialty "5-minute updates" via email
Risk Factors Associated with Methicillin Resistance among Staphylococcus aureus Infections in Veterans
Infection Control and Hospital Epidemiology, 11/25/09
Antiretroviral Drug-Resistant Mutations at Baseline and at Time of Failure of Antiretroviral Therapy in HIV Type 1-Coinfected TB Patients
AIDS Research and Human Retroviruses, 11/24/09
Protein Kinase A Activation Confers Resistance to Trastuzumab in Human Breast Cancer Cell Lines
Clinical Cancer Research, 11/20/09
Sponsor
Article Search
Sponsor


See Latest Articles


