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Your Article Summary
Justification of the starting dose as the main determinant of accrual time in dose-seeking oncology phase 1 trials
Investigational New Drugs, 10/08/09
Penel N et al. – Few parameters influence the accrual time of dose–escalation phase–1 trials. Real first–in–man phase 1 studies based on starting dose estimated from animal toxicological data require longer accrual time.
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