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See Latest ArticlesLovastatin overcomes gefitinib resistance in human non-small cell lung cancer cells with K-Ras mutations
Investigational New Drugs, 10/08/09
Park IH et al. – Lovastatin can overcome gefitinib resistance, in NSCLC cells with K–Ras mutations, by down regulation of RAS protein, which leads to inhibition of both RAF/ERK and AKT pathways.
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A Conserved Motif in the Membrane Proximal C-Terminal Tail of Human Muscarinic M1 Acetylcholine Receptors Affects Plasma Membrane Expression
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Today in Drug Resistance...keeping you current
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