Pharmacy Medical News about Antineoplastic Agents

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Evaluation of molecular descriptors for antitumor drugs with respect to noncovalent binding to DNA and antiproliferative activity
BMC Pharmacology, 09/28/09

Portugal J – For drugs binding reversibly to DNA, both their strength of binding and their cytoxicity are fairly predicted from molecular descriptors by using multiple regression methods. The equations derived may be useful for rational drug design. The results obtained agree with that compounds more active across the National Cancer Institute's 60–cell line data set tend to have common structural features.

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Guidance Values for Surface Monitoring of Antineoplastic Drugs in German Pharmacies
Annals of Occupational Hygiene, 10/27/09 Relevance Score: 64%

Triple-negative breast cancer—current status and future directions
Annals of Oncology, 11/16/09 Relevance Score: 45%

Use of remifentanil as a sedative agent in critically ill adult patients: a meta-analysis
Anaesthesia, 11/11/09 Relevance Score: 45%

The Impact of Bittering Agents on Pediatric Ingestions of Antifreeze
Clinical Pediatrics, 10/26/09 Relevance Score: 45%

The role of urate and xanthine oxidase in vascular oxidative stress: future directions
Therapeutics and Clinical Risk Management, 10/07/09 Relevance Score: 45%