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The role of tramadol ER in the treatment of chronic pain
International Journal of Clinical Practice, 09/16/2009
Review Article
Rosenberg MT – For the patient with chronic pain requiring analgesic treatment for an extended period of time, long–acting analgesics are recommended. Theoretically, these agents will provide sustained analgesia by minimising the end–of–dose pain that is often seen with short–acting medications, with improved patient convenience and a potential for reduced risk of adverse events. The extended–release formulation of tramadol (tramadol ER) has proven efficacy in chronic pain conditions such as osteoarthritis and low back pain, as well as a favourable tolerability profile. In addition, tramadol ER has been shown in clinical trials to improve pain–related sleep disturbances and physical function in patients with chronic pain from osteoarthritis and low back pain.
