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Post-infarct Treatment with Oxytocin Improves Cardiac Function and Remodeling via Activating Cell-survival Signals and Angiogenesis
Journal of Cardiovascular Pharmacology, 09/16/09
Kobayashi H et al. – Post–infarct treatment with oxytocin reduces myocardial infarct size and improves LV function and remodeling by activating oxytocin receptors and prosurvival signals and by exerting antifibrotic and angiogenic effects through activation of MMP–1, eNOS, and VEGF. These findings provide new insight into therapeutic strategies for ischemic heart disease.
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