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KU135, a Novel Novobiocin-derived C-terminal Inhibitor of Hsp90, Exerts Potent Antiproliferative Effects in Human Leukemic Cells
Molecular Pharmacology, 09/17/09
Shelton SN et al. – The data suggest that KU135 inhibits cell proliferation by regulating signaling pathways that are mechanistically different from those targeted by 17–AAG and as such represents a novel opportunity for Hsp90 inhibition.
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