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See Latest ArticlesThe effect on sotrastaurin pharmacokinetics of strong CYP3A inhibition by ketoconazole
British Journal of Clinical Pharmacology, 09/08/09
Kovarik JM et al. – The strong CYP3A4 inhibitor ketoconazole increased sotrastaurin AUC by 4.6–fold. A compensatory reduction in the dose of sotrastaurin is warranted when strong CYP3A4 inhibitors are co–administered.
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