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Pharmacogenomics in chemotherapy for GI tract cancer
Journal of Gastroenterology, 09/08/09
Furuta T et al. – In GI–tract cancer chemotherapy, 5–FU, gemcitabine, taxanes (docetaxel and paclitaxel), platinum (cisplatin and oxaliplatin) and irinotecan are often used, and molecular targeting therapy has also been developed. The respective PGx markers to such agents have been reported. Of the candidate PGx markers, K–ras mutation and UGT1A1 polymorphisms have sufficient evidence to justify routine clinical assessment for the selection of anti–cancer regimens.
Today in Drug Interactions...keeping you current
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A Randomized, Double-Blind Study Examining the Comparative Efficacies and Safety of Inhaled Epinephrine and Nasal Decongestant in Hospitalized Infants With Acute Bronchiolitis
The Pediatric Infectious Disease Journal, 11/17/09
Nifekalant versus lidocaine for in-hospital shock-resistant ventricular fibrillation or tachycardia
Resuscitation, 11/18/09
Effects of clozapine and olanzapine on cortical thickness in childhood-onset schizophrenia
Schizophrenia Research, 11/17/09
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Salix Receives FDA Marketing Approval for Metozolv
Salix Pharmaceuticals, 09/10/09
Methotrexate for maintenance of remission in Crohn's disease
Cochrane Reviews, 10/27/09
Management of chronic hepatitis C patients who have relapsed or not responded to pegylated interferon alfa plus ribavirin
Journal of Viral Hepatitis, 11/09/09
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