Pharmacy Medical News about Parkinson's disease; rasagiline; cost effectiveness

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Cost Effectiveness of Rasagiline and Pramipexole as Treatment Strategies in Early Parkinson's Disease in the UK Setting: An Economic Markov Model Evaluation
Drugs & Aging, 09/14/09

Haycox A et al. – Rasagiline was the dominant strategy. Compared with pramipexole, use of the rasagiline strategy was estimated to reduce costs by 18% per patient over 5 years and was associated with an additional 10% delay in dyskinesia onset. This strategy was also found to prolong the time to levodopa initiation by 25% through a gain of 0.83 levodopa–free years. In addition, use of the rasagiline strategy was found to generate a 5% gain in QALYs over 5 years compared with the pramipexole strategy. Sensitivity analyses confirmed that the model was robust. Rasagiline represents a cost–effective alternative to pramipexole in the treatment of early PD in the UK.

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