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See Latest ArticlesEmerging role of nitrite in myocardial protection
Archives of Pharmacal Research, 09/08/09
Lefer DJ – Nitrite has long been considered an inert oxidative metabolite of nitric oxide. However, recent experimental findings strongly suggest that nitrite is a critical storage form of NO that is converted back into NO during ischemic or hypoxic events as well as under physiological conditions. Thus, the conversion of nitrite into NO during cellular stress may be an evolutionarily conserved and redundant means for NO generation at a time when endothelial nitric oxide synthase is non–functional.
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