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See Latest ArticlesClinical risk management of Stevens-Johnson syndrome/toxic epidermal necrolysis spectrum
Dermatologic Therapy, 09/08/09
Shear NH et al. – Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but potentially life–threatening reactions to medications. Risk management should be considered prior to starting, during, and after therapy. Prior to starting therapy, risks that need to be assessed include any specific patient groups that may be at greater risk for the development of SJS/TEN. Gene testing is in place for Chinese and Thai patients who are going to be exposed to carbamazepine. During therapy, it is important to recognize SJS/TEN as a possible adverse drug reaction. Diagnostic criteria have changed, and more data exist on drugs with an increased risk.
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