Pharmacy Medical News about Ciclosporin

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A Population Pharmacokinetic Model of Ciclosporin Applicable for Assisting Dose Management of Kidney Transplant Recipients
Clinical Pharmacokinetics, 09/11/09

Falck P et al. – A NONMEM pharmacokinetic model for ciclosporin in renal transplant recipients was successfully developed and validated for the first 3 months post–transplantation. The model showed good predictability in a new patient cohort. After further clinical validation, the model may be applicable as a clinical tool for optimizing ciclosporin dosing in renal transplant recipients in the early post–transplant period.

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Sequential phase II Southwest Oncology Group studies (S0112 and S0301) of daunorubicin and cytarabine by continuous infusion, without and with ciclosporin, in older patients with previously untreated acute myeloid leukaemia
British Journal of Haematology, 10/16/09 Relevance Score: 84%

Limited Sampling Models and Bayesian Estimation for Mycophenolic Acid Area under the Curve Prediction in Stable Renal Transplant Patients Co-Medicated with Ciclosporin or Sirolimus
Clinical Pharmacokinetics, 10/15/09 Relevance Score: 80%