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See Latest ArticlesClinical Pharmacokinetics and Pharmacodynamics of Tigecycline
Clinical Pharmacokinetics, 09/09/09
Barbour A et al. – The pharmacokinetics of tigecycline are complex with both linear and non–linear characteristics. The reason for this complexity is still not fully understood. Non–linearity can be found in the volume of distribution possibly due to extensive and variable tissue and/or plasma protein binding. In contrast, clearance and area under the plasma concentration–time curve are dose–independent.
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