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See Latest ArticlesRole of N-methyl-D-aspartate receptor antagonists in postoperative pain management
Current Opinion in Anesthesiology, 09/04/09
Suzuki M – The co–administration of ketamine and morphine as a mixture is not recommended for postoperative pain relief. As an adjunct in multimodal analgesia, low–dose ketamine infusion and the administration of dextromethorphan may be able to improve postoperative pain status. Memantine exhibits the greatest potency among NMDA receptor antagonists. In future, research should consider the perioperative infusion of ketamine followed by long–term administration of memantine for the prevention of persistent pain.
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