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Deferasirox pharmacokinetics in patients with adequate vs. inadequate response
Blood, 09/17/09
Chirnomas D et al. – Tens of thousands of transfusion–dependent (e.g., thalassemia) patients worldwide suffer from chronic iron–overload and its potentially fatal complications. The oral iron chelator, deferasirox became commercially available in many countries since 2006. Effective dosing regimens for inadequately responding patients to deferasirox must be determined.
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