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The efficacy of oral ondansetron and dexamethasone for the prevention of acute chemotherapy-induced nausea and vomiting associated with moderately emetogenic chemotherapy – a retrospective audit
European Journal of Cancer Care, 09/09/09
Ng W et al. – The optimal dose of oral ondansetron for the prevention of acute chemotherapy–induced nausea and vomiting (CINV) resulting from moderately emetogenic chemotherapy (MEC) is unknown. In this study, the use of 8 mg oral ondansetron plus 8 mg oral dexamethasone achieved control of acute emesis in 75% of all patients receiving MEC which is comparable to previously reported rates of 70–80%. The benefits of using oral pre–chemotherapy anti–emetics include reduction in the costs of drugs and nursing administration time.
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