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See Latest ArticlesParoxysmal [beta]-adrenergic Receptor-mediated Alterations in Ventricular Repolarization at Rapid Heart Rates During Inhibition of Delayed Rectifier Currents
Journal of Cardiovascular Pharmacology, 09/16/09
Overholser BR et al. – The [beta]–adrenergic receptor–mediated decrease in APD90 during IKr inhibition is reversed in the presence of IKs inhibition at rapid heart rates. IKs may serve as an important compensatory mechanism to protect against adrenergically induced arrhythmias when the repolarization reserve is depleted.
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