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Study Shows Otamixaban substantially Reduced Complications of Invasive Management of Acute Coronary Syndromes
Sanofi-aventis, 08/31/09
Sanofi–aventis announced that the investigational anti–Xa intravenous anticoagulant otamixaban reduced by 27 to 42 percent the odds of the composite primary endpoint of death, myocardial infarction, urgent revascularization or rescue GPIIb/IIIa use in 4 out of the 5 otamixaban tested doses, versus standard UFH/eptifibatide combination in ACS patients suitable for invasive strategy. The results of the SEPIA–ACS1/ TIMI–42 were presented at the plenary session of the Annual European Society of Cardiology congress in Barcelona and simultaneously published online in The Lancet.
Today in Cardiac/Hypertension...keeping you current
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The role of pulmonary veins in atrial fibrillation
Pharmacology & Therapeutics, 11/24/09
Telmisartan prevents cardiovascular events in a broad group of at-risk patients
Expert Opinion in Pharmacotherapy, 11/23/09
Chronic nitrate therapy is associated with different presentation and evolution of acute coronary syndromes: insights from 52 693 patients in the Global Registry of Acute Coronary Events
European Heart Journal, 11/23/09
Today in Dosing...keeping you current
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Impact of pharmaceutical dosage form on stability and dissolution of roxithromycin
Central European Journal of Medicine, 11/24/09
Postoperative analgesia with minidose intrathecal morphine for bipolar hip prosthesis in extremely elderly patients
Journal of Anesthesia, 11/24/09
Pharmacodynamics of low molecular weight heparin in patients undergoing bariatric surgery: A prospective, randomised study comparing two doses of parnaparin (BAFLUX STUDY)
Thrombosis Research, 11/24/09
Today in Drug Interactions...keeping you current
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Gene-gene interactions in folate and adenosine biosynthesis pathways affect methotrexate efficacy and tolerability in rheumatoid arthritis
Pharmacogenetics and genomics, 11/23/09
Antiretroviral and Immunosuppressive Drug-Drug Interactions in Human Immunodeficiency Virus-Infected Liver and Kidney Transplant Recipients
Transplantation Proceedings, 11/20/09
If the KI is defined by the free energy of binding to P-gp, what kinetic parameters define the IC50 for the MDCKII-hMDR1 confluent cell monolayer
Drug Metabolism and Disposition, 11/20/09
Today in Major Studies...keeping you current
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A Multicenter, Double-Blind, Randomized, Parallel Group Study Comparing Polyvinyl Chloride and Polyvinyl Chloride-Free Catheter Materials
The Journal of Urology, 11/24/09
Carboplatin-Pemetrexed Adjuvant Chemotherapy in Resected Non-small Cell Lung Cancer (NSCLC): A Phase II Study
Anticancer Research, 11/16/09
Pivotal Data Published in the Journal Cancer Demonstrate that TREANDA Induced Durable Responses in Relapsed Indolent Non-Hodgkins Lymphoma
Cephalon, 11/06/09
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