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See Latest ArticlesCalpain activation by hepatitis C virus proteins inhibits the extrinsic apoptotic signaling pathway
Hepatology, 08/31/09
Hibner U et al. – Calpains activated by HCV proteins degrade Bid and thus dampen apoptotic signaling. These results suggest that inhibiting calpains could lead to an improved efficiency of immune–mediated elimination of HCV–infected cells.
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