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Argatroban Dosage Requirements and Outcomes in Intensive Care versus Non–Intensive Care Patients
Pharmacotherapy, 08/26/09
Smythe MA et al. – Both ICU and non–ICU patients require less than the manufacturer–recommended initial dosage of argatroban. However, ICU patients appear to be at an increased risk for bleeding and thrombotic events despite their attainment of therapeutic aPTTs.
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