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See Latest ArticlesTargeted detoxification of selected reactive oxygen species in the vascular endothelium
Journal of Pharmacology and Experimental Therapeutics, 08/21/09
Shuvaev VV et al. – This outcome agrees with reports implicating superoxide and peroxynitrite in altered endothelium–dependent vasodilatation in hypertension. Therefore, the use of endothelial cell–targeted antioxidants identifies the key specific species of ROS involved in various forms of vascular disease and holds promise for the mechanistically–tailored treatment of these pathologies.
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