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See Latest ArticlesIntracluster correlation adjustments to maintain power in cluster trials for binary outcomes
Contemporary Clinical Trials , 08/24/09
Chakraborty H et al. – The first simulation results suggest that the ICC value depends upon the event rate and event rate variations in addition to the cluster size, cluster size variations, and number of clusters. The second simulation exercise suggested that adjusting the sample size will help to preserve the appropriate power at the end of the trial.
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