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See Latest ArticlesHDL Therapy for the Treatment of Cardiovascular Diseases
Current Vascular Pharmacology, 08/24/09
Parolini C et al. – In vitro and in vivo experiments have provided mechanistic explanations for the atheroprotective effects of HDL. HDL not only mediates reverse cholesterol transport, but also exerts antioxidant, anti–inflammatory, antithrombotic and vasodilatory effects. These multiple antiatherosclerotic properties provide an excellent rationale for designing therapeutic interventions targeted at enhancing HDL/apoA–I levels, but also for considering a direct administration of HDL–apoA–I in a variety of cardiovascular diseases.
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