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Epigenetics: New Concepts of Old Phenomena in Vascular Physiology
Current Vascular Pharmacology, 08/24/09
Krause B et al. – The development of the vascular system is strongly influenced by epigenetic mechanisms. For that reason vascular cells are good candidates to be explored regarding epigenetic programming since its proved susceptibility to be imprinted. This has been described in pregnancy diseases such as intra–uterine growth restriction, gestational diabetes and pre–eclampsia, where changes in vascular function are preserved in vitro.
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