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A systematic review and meta-analysis on the therapeutic equivalence of statins
Journal of Clinical Pharmacy and Therapeutics, 08/19/09
Weng TC et al. – The only two statins that could reduce LDL–C more than 40% were rosuvastatin and atorvastatin at a daily dose of 20 mg or higher. Meta–analysis indicated a statistically significant but clinically minor difference between statins in cholesterol lowering effect. Comparisons of coronary heart disease prevention and safety could not be made because of insufficient data. At comparable doses, statins are therapeutically equivalent in reducing LDL–C.
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