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Reduction in Opioid-Related Adverse Events and Improvement in Function with Parecoxib followed by Valdecoxib Treatment after Non-Cardiac Surgery: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Trial
Clinical Drug Investigation, 08/13/09
Langford RM et al. – Patients receiving parecoxib/valdecoxib had less pain interference on physical functioning, required less opioid medication and experienced fewer clinically meaningful opioid–related adverse events than patients receiving placebo.
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