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The economic implications of generic substitution of antiepileptic drugs: a review of recent evidence
Expert Opinion in Pharmacotherapy, 08/14/09
Duh MS et al. – Current literature suggests statistically higher overall healthcare costs during periods of generic AED use than during periods when branded AED are used, consistently demonstrated across different countries and in both stable and unstable epilepsy patients, with more pronounced cost increases in patients receiving multiple generic versions. Brand–to–generic substitutions of AEDs do not necessarily reduce overall healthcare costs and may even increase them.
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