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Psycho-pharmacotherapy for anxiety and obsessive-compulsive disorder: the issue of prolonged barbiturate retention
Current Medical Research and Opinion, 08/13/09
Feldmann RE et al. – After switching to a barbiturate–free schedule, his condition continued to be unstable for more than 21 MPB half–lives and did not stabilize until MPB–metabolites dropped below their urinary detection limit. Considering that this article provides findings from a single patient, the authors use this experience to discuss and emphasize the importance of clinical control of barbiturates in psychiatry.
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