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Gastric mucosal injury in systemic lupus erythematosus patients receiving pulse methylprednisolone therapy
British Journal of Clinical Pharmacology, 08/19/09
Luo JC et al. – Use of NSAIDs/aspirin, but not H. pylori infection, increases gastric mucosal injury in SLE patients receiving pulse methylprednisolone therapy. Very high–dose steroids de novo seem not to induce gastric mucosal injury in these patients. A larger case–controlled study enrolling a heterogeneous population is needed to clarify the role of glucocorticoids in gastric mucosal injury.
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