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"Danger" conditions increase sulfamethoxazole-protein adduct formation in human antigen presenting cells
Journal of Pharmacology and Experimental Therapeutics, 08/10/09
Lavergne SN et al. – These results illustrate that "danger signals" enhance the formation of intracellular SMX–protein adducts in human APC. These findings might be relevant to the increased frequency of drug allergy in certain disease states.
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