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See Latest ArticlesUDP-Glucuronosyltransferases in Conjugation of 5 alpha- and 5 beta- Androstane Steroids
Drug Metabolism and Disposition, 08/10/09
Sten T et al. – The results shed new light on the substrate selectivity of individual UGTs in steroids glucuronidation. In addition they bear implications for doping analyses and its dependence of genetic polymorphism since testosterone is a precursor in the biosynthesis of all these 4 androgens, while the contribution of UGT2B17 to their glucuronidation vary greatly.
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