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See Latest ArticlesAn ion channel hypothesis to explain divergent cardiovascular safety of COX-2 inhibitors: the answer to a hotly-debated puzzle
Molecular Pharmacology, 08/05/09
Shapiro MS et al. – This Perspective discusses these findings in light of the role of KCNQ K+ channels in control of excitability in general, the "lipid imbalance theory" of COX–2 risks, and the potential for novel therapeutic modalities for cardiovascular disease focused on ion channels in vascular smooth muscle.
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