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Enhanced PPAR-gamma Expression in Monocyte/macrophages from Coronary Artery Disease Patients and possible Gender Differences
Journal of Pharmacology and Experimental Therapeutics, 08/05/09
Amoruso A et al. – These results indicate that the expression of PPAR–gamma is significantly higher in CAD patients than in healthy donors, and that, together with cytokine release, it appears to be gender–related: in fact, CAD women demonstrated the highest PPAR–gamma expression and the lowest cytokine release. Such differences may in part modulate the response to PPAR–gamma activators.
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