Pharmacy Medical News about adrenomedullin

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Novel peptide antagonists of adrenomedullin and calcitonin gene-related peptide receptors; identification, pharmacological characterization and interactions with position 74 in RAMP1/3
Journal of Pharmacology and Experimental Therapeutics, 08/05/09

Robinson SD et al. – Using receptor mutagenesis authors also determined that the C–terminal nine amino acids of AM appear to be responsible for its interaction with Glu 74 of RAMP3. The authors provide new information on the structure–activity relationship of AM, alpha CGRP and AM2 and how AM interacts with CGRP and AM2 receptors.

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Tolterodine extended release is well tolerated in older subjects

Evaluation of gingival crevicular fluid adrenomedullin and human neutrophil peptide 1-3 levels of patients with different periodontal disease
Journal of Periodontology, 11/06/09 Relevance Score: 84%%

The Changes of Plasma Malondialdehyde, Nitric Oxide, and Adrenomedullin Levels in Patients with Preeclampsia
Hypertension in Pregnancy, 10/30/09 Relevance Score: 80%%

Adrenomedullin is increased in alveolar macrophages and released from the lungs into the circulation in severe heart failure
Basic Research in Cardiology, 10/29/09 Relevance Score: 80%%

Calcitonin gene-related peptide, adrenomedullin and flushing
Maturitas, 10/16/09 Relevance Score: 80%%