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Effects of Selective Serotonin Reuptake Inhibitor Therapy on Endothelial Function and Inflammatory Markers in Patients With Coronary Heart Disease
Clinical Pharmacology & Therapeutics, 07/31/09
Pizzi C et al. – Sertraline treatment significantly reduced the BDI score as compared with both baseline and placebo. Levels of CRP and IL–6 also decreased after 20 weeks of sertraline treatment, whereas they did not significantly change in the placebo group. There was a significant improvement in FMD in patients on sertraline treatment, whereas there was no change in FMD in the placebo group.
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