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A role for corticotropin-releasing factor in functional gastrointestinal disorders
Current Gastroenterology Reports, 08/05/09
Tache Y et al. – Clinical studies support that CRF administration can induce IBS–like symptoms in healthy subjects and heighten colonic sensitivity in IBS patients. Yet to be ascertained is whether CRF1 receptor antagonists hold promise as a new therapy in IBS treatment.
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