Pharmacy Medical News about blepharospasm

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Long-term efficacy of botulinum toxin A for treatment of blepharospasm, hemifacial spasm, and spastic entropion: a multicentre study using two drug-dose escalation indexes
Eye, 07/27/09

Cillino S et al. – This long–term multicentre study supports a high efficacy and good safety profile of BoNT–A for treatment of BEB, HFS, and EN. The BEI indexes indicate a significantly greater BoNT–A–dose escalation for BEB patients compared with HFS or EN patients and a significantly greater BEI–% in younger vsolder BEB patients. These results confirm a greater efficacy in the elderly and provide a framework for long–term studies with a more flexible and reliable evaluation of drug–dose escalation.

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