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Differential influence of selective 5-HT5A vs 5-HT1A, 5-HT1B, or 5-HT2C receptor blockade upon light-induced phase shifts in circadian activity rhythms: Interaction studies with citalopram
European Neuropsychopharmacology, 07/16/09
Gannon RL et al. - The authors evaluated their influence on suppression of phase advances by citalopram. Its action was potentiated by WAY100635 and the 5-HT2C antagonist, SB242084, but not by A842377, SB224289, SB269970, and antagonists at 5-HT2A and 5-HT6 receptors. In conclusion, this is the first in vivo evidence for an influence of 5-HT5A receptors upon circadian rhythms, but no single class of 5-HT receptor mediates their control by citalopram.
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