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See Latest ArticlesNonsteroidal antiinflammatory drugs and risk of gastric adenocarcinoma
American Journal of Epidemiology, 07/10/09
Epplein M et al. – Study finds aspirin use to be inversely associated with distal gastric adenocarcinoma, particularly of the intestinal type.
Methods- Aim was to examine the association of gastric cancer with the use of NSAIDs
- Cases: incident gastric adenocarcinomas (n=643) identified between 1993 and 2004 among members of the Multiethnic Cohort (Hawaii and Los Angeles, California)
- Aspirin and nonaspirin NSAID use was assessed on the basis of a self-administered questionnaire
- Regular use of aspirin was associated with a decreased risk of distal gastric cancer
- However, use of nonaspirin NSAIDs was not
- The inverse association with regular aspirin use was observed only for intestinal-type distal gastric adenocarcinoma vs diffuse-type distal gastric adenocarcinoma
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