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The pharmacokinetics of fluconazole in healthy Chinese adult volunteers: influence of ethnicity and gender
Journal of Clinical Pharmacy and Therapeutics, 07/10/09
Guo T et al. - Ethnicity influences the pharmacokinetics of fluconazole tablet. However, there were statistically significant gender differences in AUC, Cmax, Vd and CL. But these could be accounted for by weight differences. If fluconazole dose-adjustment is deemed necessary, this can be done on a weight basis rather than gender basis.
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