Pharmacy Medical News about Phenytoin

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Pharmacokinetics of Phenytoin: Reminders and Discoveries
Epilepsy Currents, 07/08/09

Bergen DC - Healthy elderly adults appear to have the same phenytoin (PHT) pharmacokinetics as younger adults. Reduced PHT dosage requirements may be due to age-related changes in patients' sensitivity to the therapeutic and toxic effects of the drug. The prolonged elimination half-life suggests that most patients can take PHT once daily and the time to reach steady-state may extend to 2–3 weeks.

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Phenytoin toxicity and thyroid dysfunction
New Zealand Medical Journal, 10/08/09 Relevance Score: 89%

Unusual presentation of iatrogenic phenytoin toxicity in a newborn
Journal of Medical Toxicology, 11/11/09 Relevance Score: 88%

Phenytoin-facilitated hypoglycaemia in ESRF
British Journal of Renal Medicine, 10/26/09 Relevance Score: 88%

Utility of levetiracetam in patients with subarachnoid hemorrhage
Seizure - European Journal of Epilepsy, 10/30/09 Relevance Score: 80%

Anticonvulsant Use and Outcomes After Intracerebral Hemorrhage
Stroke, 10/08/09 Relevance Score: 80%