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See Latest ArticlesInverse Effects on Gating and Modulation Caused by a Mutation in the M2-3 Linker of the GABAA Receptor Gamma Subunit
Molecular Pharmacology, 06/25/09
O'Shea SM et al. - The authors conclude that although the gamma subunit is not required for the binding of GABA or propofol, the M2-3 linker of this subunit plays a critical role in channel gating by GABA and allosteric modulation by propofol. Results also suggest that in wild-type receptors, propofol exerts its enhancing effects by mechanisms extrinsic to channel gating.
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A Conserved Motif in the Membrane Proximal C-Terminal Tail of Human Muscarinic M1 Acetylcholine Receptors Affects Plasma Membrane Expression
Journal of Pharmacology and Experimental Therapeutics, 11/25/09
The Basic Helix-loop-helix Proteins DEC1 and DEC2 Function as Corepressors of Retinoid X Receptors
Molecular Pharmacology, 11/25/09
Control of GluR2 translational initiation by its alternative 3'UTRs
Molecular Pharmacology, 11/25/09
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