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Goutelle S et al. - The overall results suggest that the pulmonary concentrations obtained with the standard RIF dose are too low in most subjects. This work supports the need to evaluate higher doses of RIF for the treatment of patients with tuberculosis.

Today in Antimicrobials...keeping you current

A Clinical Trial of the Traditional Medicine Vernonia amygdalina in the Treatment of Uncomplicated Malaria
Journal of Alternative and Complementary Medicine, 12/01/09

Directly observed antiretroviral therapy: a systematic review and meta-analysis of randomised clinical trials
The Lancet - Early Online Publication, 11/30/09

Optimizing the treatment of chronic viral hepatitis C
Expert Review of Gastroenterology & Hepatology, 11/30/09

Today in Other Drugs...keeping you current

A single dose zoledronic acid enhances pin fixation in high tibial osteotomy using the hemicallotasis technique. A double-blind placebo controlled randomized study in 46 patients
Bone , 12/01/09

Biphasic insulin aspart in the treatment of type 2 diabetes mellitus
Expert Opinion in Pharmacotherapy, 11/30/09

Pharmacotherapy for obesity
British Journal of Clinical Pharmacology, 11/30/09

Today in Pharmacokinetics...keeping you current

Pharmacokinetics, metabolism and bioavailability of the triazole antifungal agent voriconazole in relation to CYP2C19 genotype
British Journal of Clinical Pharmacology, 11/30/09

Phase 1 Trial of Adalimumab in Focal Segmental Glomerulosclerosis (FSGS): II. Report of the FONT (Novel Therapies for Resistant FSGS) Study Group
American Journal of Kidney Diseases, 11/30/09

Effect of renal impairment on the pharmacokinetics of the GLP-1 analogue liraglutide
British Journal of Clinical Pharmacology, 11/30/09


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